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	<title>Cat grooming &#38; Cat health</title>
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		<title>Laryngeal Disease in Cats</title>
		<link>http://www.elegantkitty.com/2010/03/08/laryngeal-disease-in-cats/</link>
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		<pubDate>Mon, 08 Mar 2010 11:00:00 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[laryngeal disease]]></category>

		<category><![CDATA[laryngeal paralysis]]></category>

		<guid isPermaLink="false">tag:blogger.com,1999:blog-1170470470666539402.post-5491501005418024859</guid>
		<description><![CDATA[a href="http://www.ncbi.nlm.nih.gov/pubmed/19539507"Taylor SS, Harvey AM, Barr FJ et al: Laryngeal disease in cats: a retrospective study of 35 cases, J Feline Med Surg 11:954-962, 2009./abr /
br /
This retrospective study reviewed the medical records of 35 cats referred to the University of Bristol for investigation of laryngeal disease. Laryngeal disease is an uncommon yet important cause of dyspnea in the cat. Among the 35 cases, fourteen cats fulfilled the criteria for laryngeal paralysis (LP), 10 for neoplasia, six for inflammatory disease, and five were classified as having miscellaneous disease. The most frequently reported signs in all four groups were dyspnea, stridor and dysphonia with gagging/retching and cough occurring less frequently. Of the cats with a final diagnosis of neoplasia, four had lymphoma, four had squamous cell carcinoma, one had adenocarcinoma, and one had a poorly differentiated round cell tumor. All the cats with neoplasia were FeLV negative and three of eight cats were FIV positive. Because gross appearance of a laryngeal mass and cytology can be misleading, histopathology should always be done to make a definitive diagnosis, assist with treatment options, and offer prognostic information.  In all cases of laryngeal neoplasia in this study where cervical radiography was performed, a mass lesion was noted.  Thoracic radiography is also recommended in the investigation of LP in cats. Echolaryngography was found to be a useful and non-invasive tool to detect laryngeal masses and identify LP. Treatment for LP can either surgical or conservative and results can be variable, especially if the paralysis is bilateral versus unilateral. Cats with LP, laryngeal lymphoma, or laryngitis had excellent long-term survival following the appropriate treatment. [VT]br /
br /
bRelated articles:/bbr /
a href="http://www.ncbi.nlm.nih.gov/pubmed/16141182"Jakubiak MJ, Siedlecki CT, Zenger E et al: Laryngeal, laryngotracheal, and tracheal masses in cats: 27 cases (1998-2003), J Am Anim Hosp Assoc 41:310-316, 2005./abr /
br /
a href="http://www.ncbi.nlm.nih.gov/pubmed/19250043"Stepnik MW, Mehl ML, Hardie EM et al: Outcome of permanent tracheostomy for treatment of upper airway obstruction in cats: 21 cases (1990-2007), J Am Vet Med Assoc 234:638-643, 2009./abr /
br /
More on cat health: a href="http://www.winnfelinehealth.org/Health.html"Winn Feline Foundation Library/abr /
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			<content:encoded><![CDATA[a href="http://www.ncbi.nlm.nih.gov/pubmed/19539507"Taylor SS, Harvey AM, Barr FJ et al: Laryngeal disease in cats: a retrospective study of 35 cases, J Feline Med Surg 11:954-962, 2009./abr /
br /
This retrospective study reviewed the medical records of 35 cats referred to the University of Bristol for investigation of laryngeal disease. Laryngeal disease is an uncommon yet important cause of dyspnea in the cat. Among the 35 cases, fourteen cats fulfilled the criteria for laryngeal paralysis (LP), 10 for neoplasia, six for inflammatory disease, and five were classified as having miscellaneous disease. The most frequently reported signs in all four groups were dyspnea, stridor and dysphonia with gagging/retching and cough occurring less frequently. Of the cats with a final diagnosis of neoplasia, four had lymphoma, four had squamous cell carcinoma, one had adenocarcinoma, and one had a poorly differentiated round cell tumor. All the cats with neoplasia were FeLV negative and three of eight cats were FIV positive. Because gross appearance of a laryngeal mass and cytology can be misleading, histopathology should always be done to make a definitive diagnosis, assist with treatment options, and offer prognostic information.  In all cases of laryngeal neoplasia in this study where cervical radiography was performed, a mass lesion was noted.  Thoracic radiography is also recommended in the investigation of LP in cats. Echolaryngography was found to be a useful and non-invasive tool to detect laryngeal masses and identify LP. Treatment for LP can either surgical or conservative and results can be variable, especially if the paralysis is bilateral versus unilateral. Cats with LP, laryngeal lymphoma, or laryngitis had excellent long-term survival following the appropriate treatment. [VT]br /
br /
bRelated articles:/bbr /
a href="http://www.ncbi.nlm.nih.gov/pubmed/16141182"Jakubiak MJ, Siedlecki CT, Zenger E et al: Laryngeal, laryngotracheal, and tracheal masses in cats: 27 cases (1998-2003), J Am Anim Hosp Assoc 41:310-316, 2005./abr /
br /
a href="http://www.ncbi.nlm.nih.gov/pubmed/19250043"Stepnik MW, Mehl ML, Hardie EM et al: Outcome of permanent tracheostomy for treatment of upper airway obstruction in cats: 21 cases (1990-2007), J Am Vet Med Assoc 234:638-643, 2009./abr /
br /
More on cat health: a href="http://www.winnfelinehealth.org/Health.html"Winn Feline Foundation Library/abr /
a href="http://www.facebook.com/WinnFelineFoundation"Join us on Facebook/abr /
a href="http://www.twitter.com/WinnFeline"Follow us on Twitter/abr /
New for 2010: a href="http://www.winnfelinehealth.org/Pages/NewsletterArchive.html"subscribe to our e-newsletter/adiv class="blogger-post-footer"Providing expert cat health information and supporting cat health research since 1968.img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/1170470470666539402-5491501005418024859?l=winnfelinehealth.blogspot.com' alt='' //divdiv class="feedflare"
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		</item>
		<item>
		<title>Tritrichomonas and Reproductive Disease in Cats</title>
		<link>http://www.elegantkitty.com/2010/03/04/tritrichomonas-and-reproductive-disease-in-cats/</link>
		<comments>http://www.elegantkitty.com/2010/03/04/tritrichomonas-and-reproductive-disease-in-cats/#comments</comments>
		<pubDate>Thu, 04 Mar 2010 11:00:00 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[Tritrichomonas]]></category>

		<guid isPermaLink="false">tag:blogger.com,1999:blog-1170470470666539402.post-3807367537053796890</guid>
		<description><![CDATA[div style="color: #38761d;"bWinn-funded research/b/diva href="http://www.ncbi.nlm.nih.gov/pubmed/20043785?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=1"Gray S, Hunter S, Stone M, Gookin J. Assessment of reproductive tract disease in cats at risk for Tritrichomonas foetus infection. Am J Vet Res. 2010;71(1):76-81./abr /
br /
iTritrichomonas foetus/i is a venereal pathogen of cattle.  Since 2003, iT. foetus/i has been identified in cats as a pathogen of the gastrointestinal tract.  In cats, iT. foetus/i resides in epithelial secretions and crypts of the colon. The infection is common in purebred cats.  This study’s objective was to determine whether iT. foetus/i infection resides in reproductive tract tissues from cats housed for breeding and where a high prevalence of colonic iT. foetus/i infection has been reported. Sixty-one purebred cats in 36 catteries had reproductive tract tissue, feces, and a reproductive history evaluated. Tissues were examined for iT. foetus/i via light microscopy, immunohistochemical analysis, and PCR assay. Fifteen of 61 cats (25%) and 22 of 33 (67%) catteries were identified with active or reported iT. foetus/i infection. iT. foetus/i infection of the reproductive tract was not detected in any cats. There were also no differences in total number of litters, number of litters per breeding, kitten mortality rate, or birth defects between cats or catteries infected with iT. foetus/i and those for which iT. foetus/i infection was not identified. The authors concluded there was no evidence of reproductive tract colonization by iT. foetus/i found in this study. Therefore, it is unlikely that reproductive tract infection with iT. foetus/i plays an important role in overall disease transmission. [VT]br /
br /
bRelated articles:/bbr /
a href="http://www.ncbi.nlm.nih.gov/pubmed/19866444?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=3"Tolbert MK, Gookin J. Tritrichomonas foetus: a new agent of feline diarrhea. Compend Contin Educ Vet. 2009;31(8):374-381./abr /
br /
a href="http://www.ncbi.nlm.nih.gov/pubmed/19932359?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=2"Payne PA, Artzer M. The biology and control of Giardia spp and Tritrichomonas foetus. Vet Clin North Am Small Anim Pract. Nov 2009;39(6):993-1007, v.br /
/abr /
More on cat health: a href="http://www.ncbi.nlm.nih.gov/pubmed/19932359?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=2http://"Winn Feline Foundation Library/abr /
a href="http://www.facebook.com/WinnFelineFoundation"Join us on Facebook/abr /
a href="http://www.twitter.com/WinnFeline"Follow us on Twitter/abr /
New for 2010: a href="http://www.winnfelinehealth.org/Pages/NewsletterArchive.html"subscribe to our e-newsletter/adiv class="blogger-post-footer"Providing expert cat health information and supporting cat health research since 1968.img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/1170470470666539402-3807367537053796890?l=winnfelinehealth.blogspot.com' alt='' //divdiv class="feedflare"
a href="http://feeds.feedburner.com/~ff/CatHealthNewsFromTheWinnFelineFoundation?a=r1E_Ne_vaUg:q8Y26dOaQpI:yIl2AUoC8zA"img src="http://feeds.feedburner.com/~ff/CatHealthNewsFromTheWinnFelineFoundation?d=yIl2AUoC8zA" border="0"/img/a a href="http://feeds.feedburner.com/~ff/CatHealthNewsFromTheWinnFelineFoundation?a=r1E_Ne_vaUg:q8Y26dOaQpI:UT3xtbGYFzA"img src="http://feeds.feedburner.com/~ff/CatHealthNewsFromTheWinnFelineFoundation?d=UT3xtbGYFzA" border="0"/img/a a href="http://feeds.feedburner.com/~ff/CatHealthNewsFromTheWinnFelineFoundation?a=r1E_Ne_vaUg:q8Y26dOaQpI:qj6IDK7rITs"img src="http://feeds.feedburner.com/~ff/CatHealthNewsFromTheWinnFelineFoundation?d=qj6IDK7rITs" border="0"/img/a a href="http://feeds.feedburner.com/~ff/CatHealthNewsFromTheWinnFelineFoundation?a=r1E_Ne_vaUg:q8Y26dOaQpI:F7zBnMyn0Lo"img src="http://feeds.feedburner.com/~ff/CatHealthNewsFromTheWinnFelineFoundation?i=r1E_Ne_vaUg:q8Y26dOaQpI:F7zBnMyn0Lo" border="0"/img/a a href="http://feeds.feedburner.com/~ff/CatHealthNewsFromTheWinnFelineFoundation?a=r1E_Ne_vaUg:q8Y26dOaQpI:V_sGLiPBpWU"img src="http://feeds.feedburner.com/~ff/CatHealthNewsFromTheWinnFelineFoundation?i=r1E_Ne_vaUg:q8Y26dOaQpI:V_sGLiPBpWU" border="0"/img/a a href="http://feeds.feedburner.com/~ff/CatHealthNewsFromTheWinnFelineFoundation?a=r1E_Ne_vaUg:q8Y26dOaQpI:oCFASsrFxfc"img src="http://feeds.feedburner.com/~ff/CatHealthNewsFromTheWinnFelineFoundation?d=oCFASsrFxfc" border="0"/img/a
/divimg src="http://feeds.feedburner.com/~r/CatHealthNewsFromTheWinnFelineFoundation/~4/r1E_Ne_vaUg" height="1" width="1"/]]></description>
			<content:encoded><![CDATA[div style="color: #38761d;"bWinn-funded research/b/diva href="http://www.ncbi.nlm.nih.gov/pubmed/20043785?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=1"Gray S, Hunter S, Stone M, Gookin J. Assessment of reproductive tract disease in cats at risk for Tritrichomonas foetus infection. Am J Vet Res. 2010;71(1):76-81./abr /
br /
iTritrichomonas foetus/i is a venereal pathogen of cattle.  Since 2003, iT. foetus/i has been identified in cats as a pathogen of the gastrointestinal tract.  In cats, iT. foetus/i resides in epithelial secretions and crypts of the colon. The infection is common in purebred cats.  This study’s objective was to determine whether iT. foetus/i infection resides in reproductive tract tissues from cats housed for breeding and where a high prevalence of colonic iT. foetus/i infection has been reported. Sixty-one purebred cats in 36 catteries had reproductive tract tissue, feces, and a reproductive history evaluated. Tissues were examined for iT. foetus/i via light microscopy, immunohistochemical analysis, and PCR assay. Fifteen of 61 cats (25%) and 22 of 33 (67%) catteries were identified with active or reported iT. foetus/i infection. iT. foetus/i infection of the reproductive tract was not detected in any cats. There were also no differences in total number of litters, number of litters per breeding, kitten mortality rate, or birth defects between cats or catteries infected with iT. foetus/i and those for which iT. foetus/i infection was not identified. The authors concluded there was no evidence of reproductive tract colonization by iT. foetus/i found in this study. Therefore, it is unlikely that reproductive tract infection with iT. foetus/i plays an important role in overall disease transmission. [VT]br /
br /
bRelated articles:/bbr /
a href="http://www.ncbi.nlm.nih.gov/pubmed/19866444?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=3"Tolbert MK, Gookin J. Tritrichomonas foetus: a new agent of feline diarrhea. Compend Contin Educ Vet. 2009;31(8):374-381./abr /
br /
a href="http://www.ncbi.nlm.nih.gov/pubmed/19932359?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=2"Payne PA, Artzer M. The biology and control of Giardia spp and Tritrichomonas foetus. Vet Clin North Am Small Anim Pract. Nov 2009;39(6):993-1007, v.br /
/abr /
More on cat health: a href="http://www.ncbi.nlm.nih.gov/pubmed/19932359?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=2http://"Winn Feline Foundation Library/abr /
a href="http://www.facebook.com/WinnFelineFoundation"Join us on Facebook/abr /
a href="http://www.twitter.com/WinnFeline"Follow us on Twitter/abr /
New for 2010: a href="http://www.winnfelinehealth.org/Pages/NewsletterArchive.html"subscribe to our e-newsletter/adiv class="blogger-post-footer"Providing expert cat health information and supporting cat health research since 1968.img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/1170470470666539402-3807367537053796890?l=winnfelinehealth.blogspot.com' alt='' //divdiv class="feedflare"
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		</item>
		<item>
		<title>Treatment of Feline Asthma</title>
		<link>http://www.elegantkitty.com/2010/03/01/treatment-of-feline-asthma/</link>
		<comments>http://www.elegantkitty.com/2010/03/01/treatment-of-feline-asthma/#comments</comments>
		<pubDate>Mon, 01 Mar 2010 11:00:00 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[asthma]]></category>

		<category><![CDATA[bronchial disease]]></category>

		<category><![CDATA[bronchitis]]></category>

		<category><![CDATA[fluticasone]]></category>

		<guid isPermaLink="false">tag:blogger.com,1999:blog-1170470470666539402.post-940597264846131454</guid>
		<description><![CDATA[a href="http://www.ncbi.nlm.nih.gov/pubmed/19647461?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=1"Cohn LA, DeClue AE, Cohen RL, Reinero CR. Effects of fluticasone propionate dosage in an experimental model of feline asthma. J Feline Med Surg. 2010;12(2):91-96./abr /
br /
Feline inflammatory bronchial diseases (e.g., asthma and chronic bronchitis) are common lower respiratory diseases in cats. The mainstay of therapy for inflammatory airway disease is the administration of glucocorticoids (GCs).  Glucocorticoid use is indicated for the treatment of asthma and chronic bronchitis, yet GCs are associated with the potential for adverse side effects. Systemic side effects and the resultant adverse effects can be minimized with the use of topical application of GC to the airways via an inhalational delivery system. The authors utilized a randomized, cross-over study design to investigate the ability of three different dosages of the inhalant GC fluticasone proprionate (Flovent HFA) delivered by a metered dose inhaler to ameliorate eosinophilic airway inflammation in cats with experimentally induced allergic airway inflammation. In addition, suppression of the hypothalamic-pituitary-adrenal axis at each dose was assessed. Fluticasone was administered at dosages of 44,110, or 220 mcg administered every 12 hours to six cats. All three-dosage regimens of fluticasone resulted in significant amelioration of airway eosinophilia. None of the dose regimens tested caused HPAA suppression. The conclusion was that a twice-daily dose of 44 mcg fluticasone should be evaluated for the management of naturally occurring inflammatory bronchial disease in cats. This is important because fluticasone is a costly drug, and the lower strengths are less expensive than the higher strengths.  [VT]br /
br /
bRelated articles:/bbr /
a href="http://www.ncbi.nlm.nih.gov/pubmed/16527919?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=2"Padrid P. Use of inhaled medications to treat respiratory diseases in dogs and cats. J Am Anim Hosp Assoc. 2006;42(2):165-169./abr /
br /
a href="http://www.ncbi.nlm.nih.gov/pubmed/19339801?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=15"Reinero CR, Delgado C, Spinka C, DeClue AE, Dhand R. Enantiomer-specific effects of albuterol on airway inflammation in healthy and asthmatic cats. Int Arch Allergy Immunol. 2009;150(1):43-50./abr /
br /
More on cat health: a href="http://www.winnfelinehealth.org/Health.html"Winn Feline Foundation Library/abr /
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			<content:encoded><![CDATA[a href="http://www.ncbi.nlm.nih.gov/pubmed/19647461?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=1"Cohn LA, DeClue AE, Cohen RL, Reinero CR. Effects of fluticasone propionate dosage in an experimental model of feline asthma. J Feline Med Surg. 2010;12(2):91-96./abr /
br /
Feline inflammatory bronchial diseases (e.g., asthma and chronic bronchitis) are common lower respiratory diseases in cats. The mainstay of therapy for inflammatory airway disease is the administration of glucocorticoids (GCs).  Glucocorticoid use is indicated for the treatment of asthma and chronic bronchitis, yet GCs are associated with the potential for adverse side effects. Systemic side effects and the resultant adverse effects can be minimized with the use of topical application of GC to the airways via an inhalational delivery system. The authors utilized a randomized, cross-over study design to investigate the ability of three different dosages of the inhalant GC fluticasone proprionate (Flovent HFA) delivered by a metered dose inhaler to ameliorate eosinophilic airway inflammation in cats with experimentally induced allergic airway inflammation. In addition, suppression of the hypothalamic-pituitary-adrenal axis at each dose was assessed. Fluticasone was administered at dosages of 44,110, or 220 mcg administered every 12 hours to six cats. All three-dosage regimens of fluticasone resulted in significant amelioration of airway eosinophilia. None of the dose regimens tested caused HPAA suppression. The conclusion was that a twice-daily dose of 44 mcg fluticasone should be evaluated for the management of naturally occurring inflammatory bronchial disease in cats. This is important because fluticasone is a costly drug, and the lower strengths are less expensive than the higher strengths.  [VT]br /
br /
bRelated articles:/bbr /
a href="http://www.ncbi.nlm.nih.gov/pubmed/16527919?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=2"Padrid P. Use of inhaled medications to treat respiratory diseases in dogs and cats. J Am Anim Hosp Assoc. 2006;42(2):165-169./abr /
br /
a href="http://www.ncbi.nlm.nih.gov/pubmed/19339801?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=15"Reinero CR, Delgado C, Spinka C, DeClue AE, Dhand R. Enantiomer-specific effects of albuterol on airway inflammation in healthy and asthmatic cats. Int Arch Allergy Immunol. 2009;150(1):43-50./abr /
br /
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		</item>
		<item>
		<title>FIV and Kidney Disease in Cats</title>
		<link>http://www.elegantkitty.com/2010/02/25/fiv-and-kidney-disease-in-cats/</link>
		<comments>http://www.elegantkitty.com/2010/02/25/fiv-and-kidney-disease-in-cats/#comments</comments>
		<pubDate>Thu, 25 Feb 2010 11:00:00 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[chronic kidney disease]]></category>

		<category><![CDATA[feline immunodeficiency virus]]></category>

		<guid isPermaLink="false">tag:blogger.com,1999:blog-1170470470666539402.post-525274476678157505</guid>
		<description><![CDATA[a href="http://www.ncbi.nlm.nih.gov/pubmed/20151865?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=27"White JD, Malik R, Norris JM, Malikides N. Association between naturally occurring chronic kidney disease and feline immunodeficiency virus infection status in cats. J Am Vet Med Assoc. Feb 15 2010;236(4):424-429./abr /
br /
Chronic kidney disease (CKD) is well known in older cats. In most cases, the underlying cause is never identified. CKD appears more common in young male cats and feline immunodeficiency virus (FIV) is also common in these cats, raising the question of whether the two are related. To investigate a potential association between chronic kidney disease and FIV in cats in Australia, a case-control study was designed. The study included 73 cats with CKD and 69 cats with no evidence of CKD. All cats were tested for FIV antibodies and information on age, breed and gender was gathered. The cats were divided into two age groups - under 11 years old and over 11 years old. Statistical analysis was performed to investigate any relationship between CKD and FIV, and with the other variables. Among cats under 11 years old, those with CKD were significantly more likely to be infected with FIV than cats without CKD. It was not possible to determine if infection with FIV occurred before the cats developed CKD. The role of FIV in the development of CKD disease requires further research. [SL]br /
br /
bRelated articles:/bbr /
a href="http://www.ncbi.nlm.nih.gov/pubmed/16821485?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=2"White JD, Norris JM, Baral RM, Malik R. Naturally-occurring chronic renal disease in Australian cats: a prospective study of 184 cases. Aust Vet J. Jun 2006;84(6):188-194./abr /
br /
a href="http://www.ncbi.nlm.nih.gov/pubmed/17409007?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=5"Norris JM, Bell ET, Hales L, et al. Prevalence of feline immunodeficiency virus infection in domesticated and feral cats in eastern Australia. J Feline Med Surg. Aug 2007;9(4):300-308./abr /
br /
More on cat health: a href="http://www.winnfelinehealth.org/Health.html"Winn Feline Foundation Library/abr /
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			<content:encoded><![CDATA[a href="http://www.ncbi.nlm.nih.gov/pubmed/20151865?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=27"White JD, Malik R, Norris JM, Malikides N. Association between naturally occurring chronic kidney disease and feline immunodeficiency virus infection status in cats. J Am Vet Med Assoc. Feb 15 2010;236(4):424-429./abr /
br /
Chronic kidney disease (CKD) is well known in older cats. In most cases, the underlying cause is never identified. CKD appears more common in young male cats and feline immunodeficiency virus (FIV) is also common in these cats, raising the question of whether the two are related. To investigate a potential association between chronic kidney disease and FIV in cats in Australia, a case-control study was designed. The study included 73 cats with CKD and 69 cats with no evidence of CKD. All cats were tested for FIV antibodies and information on age, breed and gender was gathered. The cats were divided into two age groups - under 11 years old and over 11 years old. Statistical analysis was performed to investigate any relationship between CKD and FIV, and with the other variables. Among cats under 11 years old, those with CKD were significantly more likely to be infected with FIV than cats without CKD. It was not possible to determine if infection with FIV occurred before the cats developed CKD. The role of FIV in the development of CKD disease requires further research. [SL]br /
br /
bRelated articles:/bbr /
a href="http://www.ncbi.nlm.nih.gov/pubmed/16821485?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=2"White JD, Norris JM, Baral RM, Malik R. Naturally-occurring chronic renal disease in Australian cats: a prospective study of 184 cases. Aust Vet J. Jun 2006;84(6):188-194./abr /
br /
a href="http://www.ncbi.nlm.nih.gov/pubmed/17409007?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=5"Norris JM, Bell ET, Hales L, et al. Prevalence of feline immunodeficiency virus infection in domesticated and feral cats in eastern Australia. J Feline Med Surg. Aug 2007;9(4):300-308./abr /
br /
More on cat health: a href="http://www.winnfelinehealth.org/Health.html"Winn Feline Foundation Library/abr /
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New for 2010: a href="http://winnfelinehealth.us1.list-manage.com/subscribe?u=415b3f2ea14ea9e3390df93aaid=cb095b8233"subscribe to our e-newsletter/adiv class="blogger-post-footer"Providing expert cat health information and supporting cat health research since 1968.img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/1170470470666539402-525274476678157505?l=winnfelinehealth.blogspot.com' alt='' //divdiv class="feedflare"
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		</item>
		<item>
		<title>Yeast Infections in Sphynx Cats</title>
		<link>http://www.elegantkitty.com/2010/02/22/yeast-infections-in-sphynx-cats/</link>
		<comments>http://www.elegantkitty.com/2010/02/22/yeast-infections-in-sphynx-cats/#comments</comments>
		<pubDate>Mon, 22 Feb 2010 11:00:00 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[Devon Rex]]></category>

		<category><![CDATA[Malassezia]]></category>

		<category><![CDATA[Sphynx]]></category>

		<category><![CDATA[atopic dermatitis]]></category>

		<category><![CDATA[yeast]]></category>

		<guid isPermaLink="false">tag:blogger.com,1999:blog-1170470470666539402.post-5897370008730922318</guid>
		<description><![CDATA[a href="http://www.ncbi.nlm.nih.gov/pubmed/19559635?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=2"Ahman SE, Bergstrom KE. Cutaneous carriage of Malassezia species in healthy and seborrhoeic Sphynx cats and a comparison to carriage in Devon Rex cats. J Feline Med Surg. Dec 2009;11(12):970-976./abr /
br /
This study looked at the presence of Malassesia species yeast in 32 Sphynx cats and in ten domestic shorthair cats (DSH). Cutaneous colonization of large numbers of Malassezia species of yeast may be related to endocrine, immunosuppressive, neoplastic, or allergic skin disease in cats.  Devon Rex cats were recently shown to carry significantly more Malassezia species on their skin than did healthy DSH cats, and they were also predisposed to Massezia-associated seborrheic dermatitis. The Sphynx is an almost hairless cat breed and the Devon Rex was used for many years to outcross Sphynx. Seven sites on the body of each cat were tested. Malassezia species were isolated from 26/32 Sphynx cats (81%) and from 0/10 DSH control cats. All seborrheic cats had M. pachydermatitis isolated from their skin, at multiple sites.  None of the 32 Sphynx had Malassezia species isolated from the ears. Based on the location and number of yeast isolates, in Sphynx and Devon Rex, the axilla, groin, and claw fold might be more representative sites for yeast recovery and clinical significance than sampling from the ears. [VT]br /
br /
bRelated articles:/bbr /
a href="http://www.ncbi.nlm.nih.gov/pubmed/17654272?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=3"Ahman S, Perrins N, Bond R. Carriage of Malassezia spp. yeasts in healthy and seborrhoeic Devon Rex cats. Med Mycol. Aug 2007;45(5):449-455./abr /
br /
a href="http://www.ncbi.nlm.nih.gov/pubmed/17470232?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=5"Ahman S, Perrins N, Bond R. Treatment of Malassezia pachydermatis-associated seborrhoeic dermatitis in Devon Rex cats with itraconazole--a pilot study. Vet Dermatol. Jun 2007;18(3):171-174./abr /
br /
More on cat health: a href="http://www.winnfelinehealth.org/Health.html"Winn Feline Foundation Library/abr /
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			<content:encoded><![CDATA[a href="http://www.ncbi.nlm.nih.gov/pubmed/19559635?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=2"Ahman SE, Bergstrom KE. Cutaneous carriage of Malassezia species in healthy and seborrhoeic Sphynx cats and a comparison to carriage in Devon Rex cats. J Feline Med Surg. Dec 2009;11(12):970-976./abr /
br /
This study looked at the presence of Malassesia species yeast in 32 Sphynx cats and in ten domestic shorthair cats (DSH). Cutaneous colonization of large numbers of Malassezia species of yeast may be related to endocrine, immunosuppressive, neoplastic, or allergic skin disease in cats.  Devon Rex cats were recently shown to carry significantly more Malassezia species on their skin than did healthy DSH cats, and they were also predisposed to Massezia-associated seborrheic dermatitis. The Sphynx is an almost hairless cat breed and the Devon Rex was used for many years to outcross Sphynx. Seven sites on the body of each cat were tested. Malassezia species were isolated from 26/32 Sphynx cats (81%) and from 0/10 DSH control cats. All seborrheic cats had M. pachydermatitis isolated from their skin, at multiple sites.  None of the 32 Sphynx had Malassezia species isolated from the ears. Based on the location and number of yeast isolates, in Sphynx and Devon Rex, the axilla, groin, and claw fold might be more representative sites for yeast recovery and clinical significance than sampling from the ears. [VT]br /
br /
bRelated articles:/bbr /
a href="http://www.ncbi.nlm.nih.gov/pubmed/17654272?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=3"Ahman S, Perrins N, Bond R. Carriage of Malassezia spp. yeasts in healthy and seborrhoeic Devon Rex cats. Med Mycol. Aug 2007;45(5):449-455./abr /
br /
a href="http://www.ncbi.nlm.nih.gov/pubmed/17470232?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=5"Ahman S, Perrins N, Bond R. Treatment of Malassezia pachydermatis-associated seborrhoeic dermatitis in Devon Rex cats with itraconazole--a pilot study. Vet Dermatol. Jun 2007;18(3):171-174./abr /
br /
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		</item>
		<item>
		<title>Treatment of Feline Mammary Cancer</title>
		<link>http://www.elegantkitty.com/2010/02/18/treatment-of-feline-mammary-cancer-2/</link>
		<comments>http://www.elegantkitty.com/2010/02/18/treatment-of-feline-mammary-cancer-2/#comments</comments>
		<pubDate>Thu, 18 Feb 2010 11:00:00 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[adenocarcinoma]]></category>

		<category><![CDATA[doxorubicin]]></category>

		<category><![CDATA[mammary carcinoma]]></category>

		<category><![CDATA[meloxicam]]></category>

		<guid isPermaLink="false">tag:blogger.com,1999:blog-1170470470666539402.post-1917363854637704187</guid>
		<description><![CDATA[a href="http://"Borrego JF, Cartagena JC, Engel J. Treatment of feline mammary tumours using chemotherapy, surgery and a COX-2 inhibitor drug (meloxicam): a retrospective study of 23 cases (2002-2007). Veterinary and Comparative Oncology. 2009;7(4):213-221./abr /
br /
Mammary cancer is the third most common cancer in cats. It affects mainly female cats and the mean age at diagnosis is 10-12 years. Unfortunately, 90% of mammary tumors in cats are malignant. These cancers are locally invasive and metastasize to distant locations. Treatment options include radical surgery and various chemotherapy protocols, used either alone or with surgery. However, high quality data on the best treatment approach is lacking. This article evaluates the efficacy of a treatment combination of a COX-2 inhibitor (meloxicam), chemotherapy and surgery in 23 cats with mammary adenocarcinoma. All cats underwent surgery followed by doxorubicin-based chemotherapy. Meloxicam was given long-term, starting the day after surgery. Median survival time was 460 days and the median disease-free interval was 269 days. The survival times are similar to other studies, and do not show an advantage of combining meloxicam with chemotherapy and surgery. Prospective trials with larger numbers of cats are needed to find the optimal treatment for feline mammary cancer. [SL]br /
br /
bRelated articles:/bbr /
a href="http://www.ncbi.nlm.nih.gov/pubmed/19175730?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=6"McNeill CJ, Sorenmo KU, Shofer FS, et al. Evaluation of adjuvant doxorubicin-based chemotherapy for the treatment of feline mammary carcinoma. Journal of Veterinary Internal Medicine. 2009;23(1):123-129./abr /
br /
a href="http://www.ncbi.nlm.nih.gov/pubmed/16527911?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=20"Novosad CA, Bergman PJ, O'Brien M G, et al. Retrospective evaluation of adjunctive doxorubicin for the treatment of feline mammary gland adenocarcinoma: 67 cases. J Am Anim Hosp Assoc. March-April 2006;42(2):110-120./abr /
br /
Morre on cat health: a href="http://"Winn Feline Foundation Library/abr /
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/divimg src="http://feeds.feedburner.com/~r/CatHealthNewsFromTheWinnFelineFoundation/~4/RPGXihFkCJk" height="1" width="1"/]]></description>
			<content:encoded><![CDATA[a href="http://"Borrego JF, Cartagena JC, Engel J. Treatment of feline mammary tumours using chemotherapy, surgery and a COX-2 inhibitor drug (meloxicam): a retrospective study of 23 cases (2002-2007). Veterinary and Comparative Oncology. 2009;7(4):213-221./abr /
br /
Mammary cancer is the third most common cancer in cats. It affects mainly female cats and the mean age at diagnosis is 10-12 years. Unfortunately, 90% of mammary tumors in cats are malignant. These cancers are locally invasive and metastasize to distant locations. Treatment options include radical surgery and various chemotherapy protocols, used either alone or with surgery. However, high quality data on the best treatment approach is lacking. This article evaluates the efficacy of a treatment combination of a COX-2 inhibitor (meloxicam), chemotherapy and surgery in 23 cats with mammary adenocarcinoma. All cats underwent surgery followed by doxorubicin-based chemotherapy. Meloxicam was given long-term, starting the day after surgery. Median survival time was 460 days and the median disease-free interval was 269 days. The survival times are similar to other studies, and do not show an advantage of combining meloxicam with chemotherapy and surgery. Prospective trials with larger numbers of cats are needed to find the optimal treatment for feline mammary cancer. [SL]br /
br /
bRelated articles:/bbr /
a href="http://www.ncbi.nlm.nih.gov/pubmed/19175730?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=6"McNeill CJ, Sorenmo KU, Shofer FS, et al. Evaluation of adjuvant doxorubicin-based chemotherapy for the treatment of feline mammary carcinoma. Journal of Veterinary Internal Medicine. 2009;23(1):123-129./abr /
br /
a href="http://www.ncbi.nlm.nih.gov/pubmed/16527911?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=20"Novosad CA, Bergman PJ, O'Brien M G, et al. Retrospective evaluation of adjunctive doxorubicin for the treatment of feline mammary gland adenocarcinoma: 67 cases. J Am Anim Hosp Assoc. March-April 2006;42(2):110-120./abr /
br /
Morre on cat health: a href="http://"Winn Feline Foundation Library/abr /
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New for 2010: a href="http://winnfelinehealth.us1.list-manage.com/subscribe?u=415b3f2ea14ea9e3390df93aaid=cb095b8233"Subscribe to our e-newsletter/adiv class="blogger-post-footer"Providing expert cat health information and supporting cat health research since 1968.img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/1170470470666539402-1917363854637704187?l=winnfelinehealth.blogspot.com' alt='' //divdiv class="feedflare"
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		</item>
		<item>
		<title>FeLV and FIV in Germany</title>
		<link>http://www.elegantkitty.com/2010/02/15/felv-and-fiv-in-germany/</link>
		<comments>http://www.elegantkitty.com/2010/02/15/felv-and-fiv-in-germany/#comments</comments>
		<pubDate>Mon, 15 Feb 2010 11:00:00 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[feline immunodeficiency virus]]></category>

		<category><![CDATA[feline leukemia virus]]></category>

		<category><![CDATA[retrovirus]]></category>

		<guid isPermaLink="false">tag:blogger.com,1999:blog-1170470470666539402.post-3342993882373999961</guid>
		<description><![CDATA[a href="http://www.ncbi.nlm.nih.gov/pubmed/19616984?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=3"Gleich SE, Krieger S, Hartmann K. Prevalence of feline immunodeficiency virus and feline leukaemia virus among client-owned cats and risk factors for infection in Germany. J Feline Med Surg. 2009;11(12):985-992./abr /
br /
This study determined prevalence and risk factors for retrovirus infection in a large population of cats in Germany over a 10-year period. Client-owned cats (17,462) were tested for the presence of feline immunodeficiency virus (FIV) antibodies or feline leukaemia virus (FeLV) antigen. A subset of 100 cats was evaluated to determine their survival times. Of the 17,289 cats, 563 tested positive for anitibodies against FIV. The prevalence was 3.2% and did not change significantly between 1993 and 2002. FeLV antigen was found in 638 cats. The prevalence of FeLV decreased significantly during this time from 6% to 1%. Forty-two cats were positive for both viruses. Living in a multi-cat household did not influence the risk of retroviral infection. Risk factors for FIV infection were male gender, older age, mixed breed, access to outdoor, aggressive behavior, and FeLV co-infection. Risk factors for FeLV infection included contact with other cats, aggressive behavior, and FIV co-infection. Vaccination and testing programs appear to be effective in decreasing FeLV infection.  The median survival time of FIV-infected cats was not significantly different from non-infected cats. FeLV-infected cats had significantly shorter median survival times than non-infected cats.  [VT]br /
br /
bRelated articles:/bbr /
a href="http://www.ncbi.nlm.nih.gov/pubmed/19721785?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=2"Little S, Sears W, Lachtara J, Bienzle D. Seroprevalence of feline leukemia virus and feline immunodeficiency virus infection among cats in Canada. Can Vet J. 2009;50(6):644-648./abr /
br /
a href="http://www.ncbi.nlm.nih.gov/pubmed/16448357?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=34"Levy JK, Scott HM, Lachtara JL, Crawford PC. Seroprevalence of feline leukemia virus and feline immunodeficiency virus infection among cats in North America and risk factors for seropositivity. J Am Vet Med Assoc. Feb 1 2006;228(3):371-376./abr /
br /
More on cat health: a href="http://www.winnfelinehealth.org/Health.html"Winn Feline Foundation Liba href="http://www.facebook.com/WinnFelineFoundation"rary/abr /
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/divimg src="http://feeds.feedburner.com/~r/CatHealthNewsFromTheWinnFelineFoundation/~4/KZ301bAl8xI" height="1" width="1"/]]></description>
			<content:encoded><![CDATA[a href="http://www.ncbi.nlm.nih.gov/pubmed/19616984?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=3"Gleich SE, Krieger S, Hartmann K. Prevalence of feline immunodeficiency virus and feline leukaemia virus among client-owned cats and risk factors for infection in Germany. J Feline Med Surg. 2009;11(12):985-992./abr /
br /
This study determined prevalence and risk factors for retrovirus infection in a large population of cats in Germany over a 10-year period. Client-owned cats (17,462) were tested for the presence of feline immunodeficiency virus (FIV) antibodies or feline leukaemia virus (FeLV) antigen. A subset of 100 cats was evaluated to determine their survival times. Of the 17,289 cats, 563 tested positive for anitibodies against FIV. The prevalence was 3.2% and did not change significantly between 1993 and 2002. FeLV antigen was found in 638 cats. The prevalence of FeLV decreased significantly during this time from 6% to 1%. Forty-two cats were positive for both viruses. Living in a multi-cat household did not influence the risk of retroviral infection. Risk factors for FIV infection were male gender, older age, mixed breed, access to outdoor, aggressive behavior, and FeLV co-infection. Risk factors for FeLV infection included contact with other cats, aggressive behavior, and FIV co-infection. Vaccination and testing programs appear to be effective in decreasing FeLV infection.  The median survival time of FIV-infected cats was not significantly different from non-infected cats. FeLV-infected cats had significantly shorter median survival times than non-infected cats.  [VT]br /
br /
bRelated articles:/bbr /
a href="http://www.ncbi.nlm.nih.gov/pubmed/19721785?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=2"Little S, Sears W, Lachtara J, Bienzle D. Seroprevalence of feline leukemia virus and feline immunodeficiency virus infection among cats in Canada. Can Vet J. 2009;50(6):644-648./abr /
br /
a href="http://www.ncbi.nlm.nih.gov/pubmed/16448357?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=34"Levy JK, Scott HM, Lachtara JL, Crawford PC. Seroprevalence of feline leukemia virus and feline immunodeficiency virus infection among cats in North America and risk factors for seropositivity. J Am Vet Med Assoc. Feb 1 2006;228(3):371-376./abr /
br /
More on cat health: a href="http://www.winnfelinehealth.org/Health.html"Winn Feline Foundation Liba href="http://www.facebook.com/WinnFelineFoundation"rary/abr /
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		</item>
		<item>
		<title>Immune-mediated Thrombocytopenia in Cats</title>
		<link>http://www.elegantkitty.com/2010/02/11/immune-mediated-thrombocytopenia-in-cats/</link>
		<comments>http://www.elegantkitty.com/2010/02/11/immune-mediated-thrombocytopenia-in-cats/#comments</comments>
		<pubDate>Thu, 11 Feb 2010 11:00:00 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[thrombocytopenia]]></category>

		<guid isPermaLink="false">tag:blogger.com,1999:blog-1170470470666539402.post-2919326897169251811</guid>
		<description><![CDATA[a href="http://www.ncbi.nlm.nih.gov/pubmed/20045832?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=2"Wondratschek C, Weingart C, Kohn B. Primary immune-mediated thrombocytopenia in cats. J Am Anim Hosp Assoc. Jan-Feb 2010;46(1):12-19./abr /
br /
Immune-mediated thrombocytopenia (low blood platelets) is much less common in cats than in dogs. Many cases of immune-mediated thrombocytopenia (IMT) are secondary to another disease, such as viral infections, bacterial infections, inflammation, cancer, and drug therapy. Only a few primary cases of IMT (those with no known underlying diseases or contributing factors) have been described in the literature. IMT is a disease where antibodies bind to the surface of platelets, resulting in their destruction by macrophages. The diagnosis is based on a low platelet count, and exclusion of underlying diseases or triggers. Demonstration of platelet-bound antibodies using flow cytometry confirms the diagnosis, but this test is not widely available. This study, from the Free University of Berlin, describes five cats with severe IMT. All cats were presented because of spontaneous bleeding or hematoma formation. Three of the cats required transfusion with fresh whole blood; one cat also received Oxyglobin. All cats were treated with prednisolone and one cat also received chlorambucil. All cats were also treated with antibiotics to reduce the risk of secondary infections. Four of the five cats responded to treatment but one cat was euthanized due to dyspnea. [SL]br /
br /
bRelated articles:/bbr /
a href="http://www.ncbi.nlm.nih.gov/pubmed/18339567?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=15"Bianco D, Armstrong PJ, Washabau RJ. Presumed primary immune-mediated thrombocytopenia in four cats. J Feline Med Surg. Oct 2008;10(5):495-500./abr /
br /
a href="http://www.ncbi.nlm.nih.gov/pubmed/10200924?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=2"Tasker S, Mackin AJ, Day MJ. Primary immune-mediated thrombocytopenia in a cat. J Small Anim Pract. Mar 1999;40(3):127-131./abr /
br /
More on cat health: a href="http://www.winnfelinehealth.org/Health.html"Winn Feline Foundation Library/abr /
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			<content:encoded><![CDATA[a href="http://www.ncbi.nlm.nih.gov/pubmed/20045832?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=2"Wondratschek C, Weingart C, Kohn B. Primary immune-mediated thrombocytopenia in cats. J Am Anim Hosp Assoc. Jan-Feb 2010;46(1):12-19./abr /
br /
Immune-mediated thrombocytopenia (low blood platelets) is much less common in cats than in dogs. Many cases of immune-mediated thrombocytopenia (IMT) are secondary to another disease, such as viral infections, bacterial infections, inflammation, cancer, and drug therapy. Only a few primary cases of IMT (those with no known underlying diseases or contributing factors) have been described in the literature. IMT is a disease where antibodies bind to the surface of platelets, resulting in their destruction by macrophages. The diagnosis is based on a low platelet count, and exclusion of underlying diseases or triggers. Demonstration of platelet-bound antibodies using flow cytometry confirms the diagnosis, but this test is not widely available. This study, from the Free University of Berlin, describes five cats with severe IMT. All cats were presented because of spontaneous bleeding or hematoma formation. Three of the cats required transfusion with fresh whole blood; one cat also received Oxyglobin. All cats were treated with prednisolone and one cat also received chlorambucil. All cats were also treated with antibiotics to reduce the risk of secondary infections. Four of the five cats responded to treatment but one cat was euthanized due to dyspnea. [SL]br /
br /
bRelated articles:/bbr /
a href="http://www.ncbi.nlm.nih.gov/pubmed/18339567?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=15"Bianco D, Armstrong PJ, Washabau RJ. Presumed primary immune-mediated thrombocytopenia in four cats. J Feline Med Surg. Oct 2008;10(5):495-500./abr /
br /
a href="http://www.ncbi.nlm.nih.gov/pubmed/10200924?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=2"Tasker S, Mackin AJ, Day MJ. Primary immune-mediated thrombocytopenia in a cat. J Small Anim Pract. Mar 1999;40(3):127-131./abr /
br /
More on cat health: a href="http://www.winnfelinehealth.org/Health.html"Winn Feline Foundation Library/abr /
a href="http://www.facebook.com/WinnFelineFoundation"Join us on Facebook/abr /
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br /
New for 2010: a href="http://winnfelinehealth.us1.list-manage.com/subscribe?u=415b3f2ea14ea9e3390df93aaid=cb095b8233"Subscribe to our e-newsletter/adiv class="blogger-post-footer"Providing expert cat health information and supporting cat health research since 1968.img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/1170470470666539402-2919326897169251811?l=winnfelinehealth.blogspot.com' alt='' //divdiv class="feedflare"
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		</item>
		<item>
		<title>Pleural Effusion in Cats</title>
		<link>http://www.elegantkitty.com/2010/02/08/pleural-effusion-in-cats/</link>
		<comments>http://www.elegantkitty.com/2010/02/08/pleural-effusion-in-cats/#comments</comments>
		<pubDate>Mon, 08 Feb 2010 11:00:00 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[effusions]]></category>

		<category><![CDATA[exudates]]></category>

		<category><![CDATA[transudates]]></category>

		<guid isPermaLink="false">tag:blogger.com,1999:blog-1170470470666539402.post-1637980129513914701</guid>
		<description><![CDATA[a href="http://www.ncbi.nlm.nih.gov/pubmed/19539512?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=1"Zoia A, Slater LA, Heller J, Connolly DJ, Church DB. A new approach to pleural effusion in cats: markers for distinguishing transudates from exudates. J Feline Med Surg. 2009;11(10):847-855./abr /
br /
The classification of pleural effusion (PE) can be quite challenging in practice. Veterinary medicine classifies PE into transudates, modified transudates, and exudates. Human medicine utilizes just two categories, transudates and exudates. Modified transudates are defined as closely resembling an exudate based on protein content and cellularity, but resulting from increased hydrostatic pressure. Transudates are effusions from congestive heart failure (CHF). Exudates are effusions from neoplasia, pyothorax, and FIP. Chylous effusions are classified also as exudates. This study evaluated paired samples of serum and pleural fluid in 20 cats with PE for the following parameters: Light’s criteria --pleural fluid lactate dehydrogenase concentration (LDHp), pleural fluid/serum LDH ratio, pleural fluid/serum total protein ratio (TPr), pleural fluid total protein, pleural fluid cholesterol concentration, pleural fluid/serum cholesterol ratio (CHOLr), serum-effusion cholesterol gradient (CHOLg), PE total nucleated cells count (TNCCp), and pleural fluid glucose (GLUp).  In this study, nine effusions were transudates, all the result of CHF, and 11 effusions were exudates (five caused by malignancy, three by chylothorax, and three by infectious disease).  Measurement of LDHp and measurement of TPr allowed reliable classification of PEs into either transudates or exudates. Calculation of CHOLr, CHOLg, and TNCCp may help classify an exudate when there is conflict between the clinical picture and laboratory results. Measurement of serum albumin when there is a transudate may provide more information regarding the pathogenesis of the effusion. [VT]br /
br /
bRelated articles:/bbr /
a href="http://www.ncbi.nlm.nih.gov/pubmed/15825497?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=6"Hotz CS, Templeton SJ, Christopher MM. Comparative analysis of expert and machine-learning methods for classification of body cavity effusions in companion animals. J Vet Diagn Invest. 2005 Mar;17(2):158-64./abr /
br /
More on cat health: a href="http://www.winnfelinehealth.org/Health.html"Winn Feline Foundation Library/abr /
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New for 2010: a href="http://winnfelinehealth.us1.list-manage.com/subscribe?u=415b3f2ea14ea9e3390df93aaid=cb095b8233"Subscribe to our e-newsletter/adiv class="blogger-post-footer"Providing expert cat health information and supporting cat health research since 1968.img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/1170470470666539402-1637980129513914701?l=winnfelinehealth.blogspot.com' alt='' //divdiv class="feedflare"
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/divimg src="http://feeds.feedburner.com/~r/CatHealthNewsFromTheWinnFelineFoundation/~4/MjdD7CzykPk" height="1" width="1"/]]></description>
			<content:encoded><![CDATA[a href="http://www.ncbi.nlm.nih.gov/pubmed/19539512?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=1"Zoia A, Slater LA, Heller J, Connolly DJ, Church DB. A new approach to pleural effusion in cats: markers for distinguishing transudates from exudates. J Feline Med Surg. 2009;11(10):847-855./abr /
br /
The classification of pleural effusion (PE) can be quite challenging in practice. Veterinary medicine classifies PE into transudates, modified transudates, and exudates. Human medicine utilizes just two categories, transudates and exudates. Modified transudates are defined as closely resembling an exudate based on protein content and cellularity, but resulting from increased hydrostatic pressure. Transudates are effusions from congestive heart failure (CHF). Exudates are effusions from neoplasia, pyothorax, and FIP. Chylous effusions are classified also as exudates. This study evaluated paired samples of serum and pleural fluid in 20 cats with PE for the following parameters: Light’s criteria --pleural fluid lactate dehydrogenase concentration (LDHp), pleural fluid/serum LDH ratio, pleural fluid/serum total protein ratio (TPr), pleural fluid total protein, pleural fluid cholesterol concentration, pleural fluid/serum cholesterol ratio (CHOLr), serum-effusion cholesterol gradient (CHOLg), PE total nucleated cells count (TNCCp), and pleural fluid glucose (GLUp).  In this study, nine effusions were transudates, all the result of CHF, and 11 effusions were exudates (five caused by malignancy, three by chylothorax, and three by infectious disease).  Measurement of LDHp and measurement of TPr allowed reliable classification of PEs into either transudates or exudates. Calculation of CHOLr, CHOLg, and TNCCp may help classify an exudate when there is conflict between the clinical picture and laboratory results. Measurement of serum albumin when there is a transudate may provide more information regarding the pathogenesis of the effusion. [VT]br /
br /
bRelated articles:/bbr /
a href="http://www.ncbi.nlm.nih.gov/pubmed/15825497?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=6"Hotz CS, Templeton SJ, Christopher MM. Comparative analysis of expert and machine-learning methods for classification of body cavity effusions in companion animals. J Vet Diagn Invest. 2005 Mar;17(2):158-64./abr /
br /
More on cat health: a href="http://www.winnfelinehealth.org/Health.html"Winn Feline Foundation Library/abr /
a href="http://www.facebook.com/WinnFelineFoundation"Join us on Facebook/abr /
a href="http://www.twitter.com/WinnFeline"Follow us on Twitter/abr /
br /
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		</item>
		<item>
		<title>Tramadol for Treatment of Pain in Cats</title>
		<link>http://www.elegantkitty.com/2010/02/04/tramadol-for-treatment-of-pain-in-cats/</link>
		<comments>http://www.elegantkitty.com/2010/02/04/tramadol-for-treatment-of-pain-in-cats/#comments</comments>
		<pubDate>Thu, 04 Feb 2010 11:00:00 +0000</pubDate>
		<dc:creator>admin</dc:creator>
		
		<category><![CDATA[analgesia]]></category>

		<category><![CDATA[tramadol]]></category>

		<guid isPermaLink="false">tag:blogger.com,1999:blog-1170470470666539402.post-1560396244155972655</guid>
		<description><![CDATA[a href="http://www.ncbi.nlm.nih.gov/pubmed/19951117?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=1"Pypendop BH, Siao KT, Ilkiw JE. Effects of tramadol hydrochloride on the thermal threshold in cats. Am J Vet Res. Dec 2009;70(12):1465-1470./abr /
br /
Tramadol is a centrally acting analgesic agent that is increasingly being used to treat pain in cats, though limited data are available on analgesic efficacy. Six healthy adult cats were used in this study to determine the thermal antinociceptive effect of the oral administration of tramadol at doses between 0.5 and 4 mg/kg in cats. An antinociceptive effect refers to reduction of sensitivity to painful stimuli.  Results showed that doses of 2 mg/kg and higher were necessary to yield a significant and sustained effect. All six cats exhibited mydriasis (dilated pupils) after administration of 3 and 4 mg/kg. Three of the six cats appeared to have a facial itch at different doses of 2, 3, and 4 mg/kg, respectively. No clinically important adverse effect was observed in the cats though this study was not designed to assess the safety of tramadol in cats. This study suggests that a dose of 4 mg/kg given every 6 hours will maintain analgesia close to the maximum effect of tramadol. [VT]br /
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bRelated articles:/bbr /
a href="http://www.ncbi.nlm.nih.gov/pubmed/19233698?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=3"Brondani JT, Loureiro Luna SP, Beier SL, Minto BW, Padovani CR. Analgesic efficacy of perioperative use of vedaprofen, tramadol or their combination in cats undergoing ovariohysterectomy. Journal of Feline Medicine  Surgery. 2009;11(6):420-429./abr /
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a href="http://www.ncbi.nlm.nih.gov/pubmed/18177319?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=6"Pypendop BH, Ilkiw JE. Pharmacokinetics of tramadol, and its metabolite O-desmethyl-tramadol, in cats. J Vet Pharmacol Ther. Feb 2008;31(1):52-59./abr /
br /
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			<content:encoded><![CDATA[a href="http://www.ncbi.nlm.nih.gov/pubmed/19951117?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=1"Pypendop BH, Siao KT, Ilkiw JE. Effects of tramadol hydrochloride on the thermal threshold in cats. Am J Vet Res. Dec 2009;70(12):1465-1470./abr /
br /
Tramadol is a centrally acting analgesic agent that is increasingly being used to treat pain in cats, though limited data are available on analgesic efficacy. Six healthy adult cats were used in this study to determine the thermal antinociceptive effect of the oral administration of tramadol at doses between 0.5 and 4 mg/kg in cats. An antinociceptive effect refers to reduction of sensitivity to painful stimuli.  Results showed that doses of 2 mg/kg and higher were necessary to yield a significant and sustained effect. All six cats exhibited mydriasis (dilated pupils) after administration of 3 and 4 mg/kg. Three of the six cats appeared to have a facial itch at different doses of 2, 3, and 4 mg/kg, respectively. No clinically important adverse effect was observed in the cats though this study was not designed to assess the safety of tramadol in cats. This study suggests that a dose of 4 mg/kg given every 6 hours will maintain analgesia close to the maximum effect of tramadol. [VT]br /
br /
bRelated articles:/bbr /
a href="http://www.ncbi.nlm.nih.gov/pubmed/19233698?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=3"Brondani JT, Loureiro Luna SP, Beier SL, Minto BW, Padovani CR. Analgesic efficacy of perioperative use of vedaprofen, tramadol or their combination in cats undergoing ovariohysterectomy. Journal of Feline Medicine  Surgery. 2009;11(6):420-429./abr /
br /
a href="http://www.ncbi.nlm.nih.gov/pubmed/18177319?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumordinalpos=6"Pypendop BH, Ilkiw JE. Pharmacokinetics of tramadol, and its metabolite O-desmethyl-tramadol, in cats. J Vet Pharmacol Ther. Feb 2008;31(1):52-59./abr /
br /
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